Yes, you can use the VectorFog C100 Plus ULV Cold Fogger for an indoor or ourdoor fogger for mosquitoes. We would recommend that you use it with a product like Shockwave Fogging Concentrate which would provide you with a quick knockdown as well as a residual control, and also includes an IGR (Insect Growth Regulator) that stops the reproductive cycle in mosquitoes. The Shockwave would provide up to a 30 day residual however, you may only get a 14 residual out of it. UV Rays, rain, and other elements will start to break it down over time, and there is not an exact amount of time we can tell you for certain it will last. Keep in mind that Shockwave can only be used for mosquitoes right around the perimeter of the structure and not for widespread areas outdoors.